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Crystal structure of helicase PIF1 from thermus oshimai in apo form

Analyse Crystal structure of helicase PIF1 from thermus oshimai in apo form in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6S3E
Type: protein
Length: 874 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: PIF1 helicase
UniProt: K7RJ88
Pockets: 14 · best druggability 0.78

Structure

x-ray diffraction · 2 distinct chains · 28% helix, 19% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	PIF1 helicase	protein	436	32% helix, 20% strand	K7RJ88
B	PIF1 helicase	protein	438	25% helix, 17% strand	K7RJ88

Pockets

14 pockets found on a 1 Å grid, 8 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	681	0.78	0.83	59	empty
2	706	0.77	0.82	69	empty
3	108	0.69	0.91	21	empty
4	442	0.66	0.79	35	empty
5	103	0.64	0.89	14	empty

Interfaces

1 interface between chains.

A–B · 223 Å² buried · 1 hydrogen bond · protein-protein

Compared structures

6S3E · Crystal structure of helicase Pif1 from Thermus oshimai in apo form · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt K7RJ88
Elsewhere: RCSB PDB 6S3E · PDBe 6S3E · UniProt K7RJ88

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