Research workbench
Export apparatus core and inner rod of the shigella type 3 secretion system
Analyse Export apparatus core and inner rod of the shigella type 3 secretion system in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6RWY
- Type
- protein
- Length
- 3,160 residues
- Chains
- 33
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Inner rod protein; Protein mxih; Surface presentation of antigens protein spap; Surface…
- UniProt
- P0A223, P0A1L3, P0A1M6, P0A1M4
- Pockets
- 20 · best druggability 0.88
Structure
electron microscopy · 9 distinct chains · 81% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, G, H, I, J, K | Inner rod protein | protein | 59 | 88% helix, 0% strand | — |
| B, C, D, E, F | Inner rod protein | protein | 73 | 90% helix, 0% strand | — |
| L, M, N, O, P, Q, R, S, T, U, V | Protein mxih | protein | 73 | 90% helix, 0% strand | P0A223 |
| a, b, c, d, e | Surface presentation of antigens protein spap | protein | 208 | 74% helix, 0% strand | P0A1L3 |
| f | Surface presentation of antigens protein spar | protein | 240 | 72% helix, 0% strand | P0A1M6 |
| g, h | Surface presentation of antigens protein spaq | protein | 86 | 85% helix, 0% strand | P0A1M4 |
| i | Surface presentation of antigens protein spaq | protein | 75 | 89% helix, 0% strand | P0A1M4 |
| j | Surface presentation of antigens protein spaq | protein | 68 | 93% helix, 0% strand | P0A1M4 |
| k | Surface presentation of antigens protein spaq | protein | 43 | 84% helix, 0% strand | P0A1M4 |
Pockets
20 pockets found on a 1 Å grid, 20 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 625 | 0.88 | 0.93 | 94 | empty |
| 2 | 1139 | 0.86 | 0.87 | 151 | empty |
| 3 | 418 | 0.86 | 0.93 | 46 | empty |
| 4 | 397 | 0.86 | 0.93 | 49 | empty |
| 5 | 1054 | 0.85 | 0.86 | 98 | empty |
Interfaces
107 interfaces between chains.
- e–f · 2290 Ų buried · 14 hydrogen bonds · protein-protein
- a–b · 2201 Ų buried · 13 hydrogen bonds · protein-protein
- c–d · 2116 Ų buried · 16 hydrogen bonds · protein-protein
- b–c · 2030 Ų buried · 12 hydrogen bonds · protein-protein
- a–f · 1995 Ų buried · 19 hydrogen bonds · protein-protein
Compared structures
- 6RWY · Export apparatus core and inner rod of the Shigella type 3 secretion system · the same entry in another collection · chain K against K, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0A223
- Every structure of UniProt P0A1L3
- Every structure of UniProt P0A1M6
- Every structure of UniProt P0A1M4
- Elsewhere: RCSB PDB 6RWY · PDBe 6RWY · UniProt P0A223 · UniProt P0A1L3 · UniProt P0A1M6 · UniProt P0A1M4
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.