Research workbench

Crystal structure of tyrosinase pvdp from pseudomonas aeruginosa bound to copper

Analyse Crystal structure of tyrosinase pvdp from pseudomonas aeruginosa bound to copper in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6RRQ
Type: protein
Length: 896 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Pvdp
UniProt: Q9I188
Ligands: CU
Pockets: 10 · best druggability 0.87

Structure

x-ray diffraction · 2 distinct chains · 39% helix, 15% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Pvdp	protein	448	38% helix, 15% strand	Q9I188
B	Pvdp	protein	448	40% helix, 15% strand	Q9I188

Ligands and binding sites

CU · Copper (II) ion · metal · 4 copies · chains A, B
GOL · Glycerol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

10 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1045	0.87	0.88	100	empty
2	432	0.65	0.78	38	empty
3	418	0.63	0.77	42	empty
4	121	0.48	0.79	25	empty
5	133	0.47	0.77	16	empty

Interfaces

1 interface between chains.

A–B · 3014 Å² buried · 38 hydrogen bonds · protein-protein

Compared structures

6RRQ · Crystal structure of tyrosinase PvdP from Pseudomonas aeruginosa bound to copper · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9I188
Elsewhere: RCSB PDB 6RRQ · PDBe 6RRQ · UniProt Q9I188

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.