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Crystal structure of mouse cis-aconitate decarboxylase
Analyse Crystal structure of mouse cis-aconitate decarboxylase in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6R6T
- Type
- protein
- Length
- 901 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Cis-aconitate decarboxylase
- UniProt
- A0A0R4J027
- Pockets
- 8 · best druggability 0.66
Structure
x-ray diffraction · 2 distinct chains · 52% helix, 8% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Cis-aconitate decarboxylase | protein | 450 | 51% helix, 9% strand | A0A0R4J027 |
| B | Cis-aconitate decarboxylase | protein | 451 | 53% helix, 8% strand | A0A0R4J027 |
Pockets
8 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 411 | 0.66 | 0.79 | 38 | empty |
| 2 | 421 | 0.65 | 0.78 | 41 | empty |
| 3 | 156 | 0.56 | 0.81 | 23 | empty |
| 4 | 133 | 0.54 | 0.82 | 21 | empty |
| 5 | 84 | 0.36 | 0.75 | 15 | empty |
Interfaces
1 interface between chains.
- A–B · 2020 Ų buried · 34 hydrogen bonds · protein-protein
Compared structures
- 6R6T · Crystal structure of mouse cis-aconitate decarboxylase · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A0R4J027
- Elsewhere: RCSB PDB 6R6T · PDBe 6R6T · UniProt A0A0R4J027
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