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Apo structure of R504C mutant of pseudomonas aeruginosa penicillin- binding protein 3 (PBP3)

Analyse Apo structure of R504C mutant of pseudomonas aeruginosa penicillin- binding… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6R40
Type: protein
Length: 505 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Peptidoglycan D,D-transpeptidase ftsi
EC: 3.4.16.4
UniProt: G3XD46
Pockets: 3 · best druggability 0.56

Structure

x-ray diffraction · 1 distinct chain · 35% helix, 24% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Peptidoglycan D,D-transpeptidase ftsi (EC 3.4.16.4)	protein	505	35% helix, 24% strand	G3XD46

Pockets

3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	297	0.56	0.76	38	empty
2	245	0.56	0.77	37	empty
3	98	0.42	0.78	17	empty

Compared structures

6R40 · Apo structure of R504C mutant of Pseudomonas aeruginosa Penicillin-Binding Protein 3… · the same entry in another collection · chain A against A, TM-score 1.00
G3XD46 · AlphaFold monomer V2.0 prediction for peptidoglycan D,D-transpeptidase ftsi (G3XD46) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt G3XD46
Elsewhere: RCSB PDB 6R40 · PDBe 6R40 · UniProt G3XD46

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