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Crystal structure of CSX1 from sulfolobus islandicus orthorhombic form

Analyse Crystal structure of CSX1 from sulfolobus islandicus orthorhombic form in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6QZT
Type: protein
Length: 1,362 residues
Chains: 3
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: CRISPR-associated (CAS) dxthg family
UniProt: F0NE21
Pockets: 10 · best druggability 0.77

Structure

x-ray diffraction · 1 distinct chain · 51% helix, 12% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B, C	CRISPR-associated (CAS) dxthg family	protein	454	51% helix, 12% strand	F0NE21

Pockets

10 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1114	0.77	0.79	95	empty
2	61	0.71	0.97	30	empty
3	253	0.62	0.81	46	empty
4	165	0.48	0.77	36	empty
5	133	0.44	0.76	17	empty

Interfaces

1 interface between chains.

A–B · 6763 Å² buried · 86 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 9 disulfide (disulfide).

Compared structures

6QZT · Crystal structure of Csx1 from Sulfolobus islandicus orthorhombic form · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt F0NE21
Elsewhere: RCSB PDB 6QZT · PDBe 6QZT · UniProt F0NE21

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