Research workbench
Crystal structure of CSX1 from sulfolobus islandicus monoclinic form
Analyse Crystal structure of CSX1 from sulfolobus islandicus monoclinic form in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6QZQ
- Type
- protein
- Length
- 2,724 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- CRISPR-associated (CAS) dxthg family
- UniProt
- F0NE21
- Pockets
- 20 · best druggability 0.75
Structure
x-ray diffraction · 1 distinct chain · 50% helix, 8% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D, E, F | CRISPR-associated (CAS) dxthg family | protein | 454 | 50% helix, 8% strand | F0NE21 |
Pockets
20 pockets found on a 1 Å grid, 11 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1029 | 0.75 | 0.78 | 102 | empty |
| 2 | 938 | 0.73 | 0.77 | 62 | empty |
| 3 | 63 | 0.73 | 0.99 | 16 | empty |
| 4 | 62 | 0.70 | 0.97 | 21 | empty |
| 5 | 50 | 0.69 | 0.98 | 19 | empty |
Interfaces
9 interfaces between chains.
- E–F · 6802 Ų buried · 78 hydrogen bonds · protein-protein
- A–B · 6717 Ų buried · 69 hydrogen bonds · protein-protein
- C–D · 6710 Ų buried · 77 hydrogen bonds · protein-protein
- C–E · 288 Ų buried · 2 hydrogen bonds · protein-protein
- B–F · 232 Ų buried · 0 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 18 disulfide (disulfide).
Compared structures
- 6QZQ · Crystal structure of Csx1 from Sulfolobus islandicus monoclinic form · the same entry in another collection · chain E against E, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt F0NE21
- Elsewhere: RCSB PDB 6QZQ · PDBe 6QZQ · UniProt F0NE21
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.