Research workbench
Crystal structure of the SKI2 RNA-helicase BRR2 from chaetomium thermophilum in the apo state
Analyse Crystal structure of the SKI2 RNA-helicase BRR2 from chaetomium thermophilum in… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6QWS
- Type
- protein
- Length
- 1,680 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Pre-mRNA splicing helicase-like protein
- UniProt
- G0S0B9
- Ligands
- SO4
- Pockets
- 20 · best druggability 0.86
Structure
x-ray diffraction · 1 distinct chain · 43% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Pre-mRNA splicing helicase-like protein | protein | 1680 | 43% helix, 16% strand | G0S0B9 |
Ligands and binding sites
- SO4 · Sulfate ion · ion · 6 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
20 pockets found on a 1 Å grid, 14 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 994 | 0.86 | 0.87 | 106 | empty |
| 2 | 769 | 0.82 | 0.85 | 67 | empty |
| 3 | 216 | 0.73 | 0.89 | 31 | empty |
| 4 | 306 | 0.73 | 0.86 | 41 | SO4 |
| 5 | 516 | 0.69 | 0.79 | 54 | SO4 |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt G0S0B9
- Elsewhere: RCSB PDB 6QWS · PDBe 6QWS · UniProt G0S0B9
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