Research workbench
TT_C0855 competence pilin from thermus thermophilus HB27
Analyse TT_C0855 competence pilin from thermus thermophilus HB27 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6QVF
- Type
- protein
- Length
- 687 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Prepilin-like protein
- UniProt
- Q8KPZ3
- Pockets
- 6 · best druggability 0.81
Structure
x-ray diffraction · 4 distinct chains · 29% helix, 28% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Prepilin-like protein | protein | 171 | 28% helix, 28% strand | Q8KPZ3 |
| B | Prepilin-like protein | protein | 173 | 29% helix, 29% strand | Q8KPZ3 |
| C | Prepilin-like protein | protein | 170 | 28% helix, 28% strand | Q8KPZ3 |
| D | Prepilin-like protein | protein | 173 | 30% helix, 28% strand | Q8KPZ3 |
Pockets
6 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 864 | 0.81 | 0.84 | 90 | empty |
| 2 | 441 | 0.65 | 0.78 | 53 | empty |
| 3 | 238 | 0.59 | 0.80 | 34 | empty |
| 4 | 183 | 0.56 | 0.80 | 20 | empty |
| 5 | 173 | 0.55 | 0.80 | 21 | empty |
Interfaces
6 interfaces between chains.
- A–B · 1004 Ų buried · 14 hydrogen bonds · protein-protein
- C–D · 993 Ų buried · 15 hydrogen bonds · protein-protein
- A–D · 620 Ų buried · 8 hydrogen bonds · protein-protein
- A–C · 610 Ų buried · 7 hydrogen bonds · protein-protein
- B–D · 609 Ų buried · 7 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 8 disulfide (disulfide).
Compared structures
- 6QVF · TT_C0855 competence pilin from Thermus thermophilus HB27 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8KPZ3
- Elsewhere: RCSB PDB 6QVF · PDBe 6QVF · UniProt Q8KPZ3
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