Research workbench
Two seven-bladed beta-propeller domains revealed by the structure of a C. elegans homologue of yeast actin interacting protein 1 (AIP1).
Analyse Two seven-bladed beta-propeller domains revealed by the structure of a C.… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1NR0
- Type
- protein
- Length
- 610 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Actin interacting protein 1
- UniProt
- Q11176
- Ligands
- MN
- Pockets
- 6 · best druggability 0.79
Structure
x-ray diffraction · 1 distinct chain · 1% helix, 50% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Actin interacting protein 1 | protein | 610 | 1% helix, 50% strand | Q11176 |
Ligands and binding sites
- MN · Manganese (II) ion · metal · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 802 | 0.79 | 0.82 | 63 | empty |
| 2 | 472 | 0.77 | 0.85 | 46 | MN |
| 3 | 135 | 0.56 | 0.83 | 22 | empty |
| 4 | 182 | 0.48 | 0.76 | 29 | empty |
| 5 | 51 | 0.39 | 0.82 | 16 | empty |
Compared structures
- 1NR0 · Two Seven-Bladed Beta-Propeller Domains Revealed By The Structure Of A C. elegans… · the same entry in another collection · chain A against A, TM-score 1.00
- Q11176 · AlphaFold monomer V2.0 prediction for actin-interacting protein 1 (Q11176) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q11176
- Elsewhere: RCSB PDB 1NR0 · PDBe 1NR0 · UniProt Q11176
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