Research workbench
Pcff from enterococcus faecalis PCF10
Analyse Pcff from enterococcus faecalis PCF10 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6QEQ
- Type
- protein
- Length
- 436 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Pcff
- UniProt
- Q5G3N6
- Pockets
- 4 · best druggability 0.79
Structure
x-ray diffraction · 4 distinct chains · 70% helix, 11% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Pcff | protein | 111 | 70% helix, 11% strand | Q5G3N6 |
| B | Pcff | protein | 111 | 71% helix, 11% strand | Q5G3N6 |
| C | Pcff | protein | 105 | 70% helix, 11% strand | Q5G3N6 |
| D | Pcff | protein | 109 | 68% helix, 11% strand | Q5G3N6 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 945 | 0.79 | 0.81 | 86 | empty |
| 2 | 103 | 0.48 | 0.81 | 24 | empty |
| 3 | 87 | 0.44 | 0.80 | 18 | empty |
| 4 | 83 | 0.42 | 0.79 | 19 | empty |
Interfaces
6 interfaces between chains.
- A–C · 3619 Ų buried · 44 hydrogen bonds · protein-protein
- B–D · 3606 Ų buried · 46 hydrogen bonds · protein-protein
- A–B · 963 Ų buried · 14 hydrogen bonds · protein-protein
- B–C · 277 Ų buried · 2 hydrogen bonds · protein-protein
- A–D · 123 Ų buried · 1 hydrogen bond · protein-protein
Modifications
Observed in the structure: 4 modified (engineered).
Compared structures
- 6QEQ · PcfF from Enterococcus faecalis pCF10 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5G3N6
- Elsewhere: RCSB PDB 6QEQ · PDBe 6QEQ · UniProt Q5G3N6
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