Research workbench

Lysine decarboxylase a from pseudomonas aeruginosa

Analyse Lysine decarboxylase a from pseudomonas aeruginosa in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6Q6I
Type: protein
Length: 749 residues
Chains: 1
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Biodegradative arginine decarboxylase
EC: 4.1.1.19, 4.1.1.18
UniProt: A0A071KXD7
Ligands: PLP
Pockets: 8 · best druggability 0.65

Structure

electron microscopy · 1 distinct chain · 28% helix, 12% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Biodegradative arginine decarboxylase (EC 4.1.1.19, 4.1.1.18)	protein	749	28% helix, 12% strand	A0A071KXD7

Ligands and binding sites

PLP · Pyridoxal-5'-phosphate · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

8 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	218	0.65	0.83	38	PLP
2	376	0.61	0.77	44	empty
3	199	0.52	0.78	27	empty
4	80	0.50	0.83	24	empty
5	110	0.48	0.80	22	empty

Modifications

Observed in the structure: 1 cofactor (pyridoxal phosphate Schiff base).

Compared structures

6Q6I · Lysine decarboxylase A from Pseudomonas aeruginosa · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A071KXD7
Elsewhere: RCSB PDB 6Q6I · PDBe 6Q6I · UniProt A0A071KXD7

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.