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Structure of the parallel-stranded DNA quadruplex D(TTAGGGA)4 containing the human telomeric repeat

Analyse Structure of the parallel-stranded DNA quadruplex D(TTAGGGA)4 containing the… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
1NP9
Type
DNA
Length
28 nucleotides
Chains
4
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
5'-D(*TP*TP*AP*GP*GP*GP*T)-3'

Structure

solution nmr · 1 distinct chain.

ChainMoleculeTypeResiduesSecondary structureUniProt
A, B, C, D5'-D(*TP*TP*AP*GP*GP*GP*T)-3'dna7——

Interfaces

6 interfaces between chains.

  • B–C · 374 Ų buried · 22 hydrogen bonds · nucleic-nucleic
  • A–D · 372 Ų buried · 22 hydrogen bonds · nucleic-nucleic
  • C–D · 327 Ų buried · 21 hydrogen bonds · nucleic-nucleic
  • A–B · 265 Ų buried · 17 hydrogen bonds · nucleic-nucleic
  • A–C · 163 Ų buried · 1 hydrogen bond · nucleic-nucleic

Compared structures

  • 1NP9 · Structure of the parallel-stranded DNA quadruplex d(TTAGGGA)4 containing the human… · the same entry in another collection · chain A against A, TM-score 1.00

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