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Crystal structure of laccase from thermus thermophilus HB27 with an open conformation of beta-hairpin (average deposted dose 2.5 mgy)

Analyse Crystal structure of laccase from thermus thermophilus HB27 with an open… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6Q29
Type: protein
Length: 439 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Laccase
EC: 1.10.3.2
UniProt: Q72HW2
Ligands: CU
Pockets: 6 · best druggability 0.73

Structure

x-ray diffraction · 1 distinct chain · 6% helix, 45% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Laccase (EC 1.10.3.2)	protein	439	6% helix, 45% strand	Q72HW2

Ligands and binding sites

CU · Copper (II) ion · metal · 2 copies · chains A
PG4 · Tetraethylene glycol · additive · chains A
PGE · Triethylene glycol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

6 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	58	0.73	0.97	17	empty
2	288	0.61	0.79	30	PG4
3	216	0.53	0.77	35	empty
4	142	0.51	0.80	27	empty
5	58	0.40	0.81	11	empty

Compared structures

6Q29 · Crystal structure of Laccase from Thermus thermophilus HB27 with an open conformation of… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q72HW2
Elsewhere: RCSB PDB 6Q29 · PDBe 6Q29 · UniProt Q72HW2

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