Research workbench

X-ray structure of erabutoxin C, a dimeric neurotoxin

Analyse X-ray structure of erabutoxin C, a dimeric neurotoxin in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6PNW
Type: protein
Length: 124 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Erabutoxin C
UniProt: Q7T2I5
Pockets: 1 · best druggability 0.40

Structure

x-ray diffraction · 1 distinct chain · 0% helix, 44% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Erabutoxin C	protein	62	0% helix, 44% strand	Q7T2I5

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	126	0.40	0.75	25	empty

Interfaces

1 interface between chains.

A–B · 317 Å² buried · 7 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 8 disulfide (disulfide).

Compared structures

6PNW · X-ray structure of erabutoxin C, a dimeric neurotoxin · the same entry in another collection · chain A against A, TM-score 1.00
Q7T2I5 · AlphaFold monomer V2.0 prediction for erabutoxin C (Q7T2I5) · a predicted model of the same protein · chain B against A, TM-score 0.94

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q7T2I5
Elsewhere: RCSB PDB 6PNW · PDBe 6PNW · UniProt Q7T2I5

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