Research workbench
Engineered single chain antibody C9+C14 scfv
Analyse Engineered single chain antibody C9+C14 scfv in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6P79
- Type
- protein
- Length
- 227 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Engineered antibody heavy chain; Engineered antibody light chain
- Pockets
- 3 · best druggability 0.44
Structure
x-ray diffraction · 2 distinct chains · 7% helix, 51% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| H | Engineered antibody heavy chain | protein | 119 | 10% helix, 53% strand | — |
| L | Engineered antibody light chain | protein | 108 | 3% helix, 49% strand | — |
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 145 | 0.44 | 0.76 | 27 | empty |
| 2 | 59 | 0.30 | 0.75 | 17 | empty |
| 3 | 50 | 0.24 | 0.72 | 17 | empty |
Interfaces
1 interface between chains.
- H–L · 922 Ų buried · 8 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 2 disulfide (disulfide).
Compared structures
- 6P79 · Engineered single chain antibody C9+C14 ScFv · the same entry in another collection · chain H against H, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 6P79 · PDBe 6P79
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