Research workbench
Structure of staphylococcus aureus RNase P protein mutant with defective mRNA degradation activity
Analyse Structure of staphylococcus aureus RNase P protein mutant with defective mRNA… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6OV1
- Type
- protein
- Length
- 241 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ribonuclease P protein component
- EC
- 3.1.26.5
- UniProt
- P0A0H5
- Pockets
- 3 · best druggability 0.40
Structure
x-ray diffraction · 2 distinct chains · 50% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ribonuclease P protein component (EC 3.1.26.5) | protein | 118 | 53% helix, 19% strand | P0A0H5 |
| B | Ribonuclease P protein component (EC 3.1.26.5) | protein | 123 | 48% helix, 20% strand | P0A0H5 |
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 121 | 0.40 | 0.75 | 13 | empty |
| 2 | 110 | 0.40 | 0.75 | 20 | empty |
| 3 | 67 | 0.31 | 0.74 | 11 | empty |
Interfaces
1 interface between chains.
- A–B · 407 Ų buried · 9 hydrogen bonds · protein-protein
Compared structures
- 6OV1 · Structure of Staphylococcus aureus RNase P protein mutant with defective mRNA degradation… · the same entry in another collection · chain A against A, TM-score 1.00
- P0A0H5 · AlphaFold monomer V2.0 prediction for ribonuclease P protein component (P0A0H5) · a predicted model of the same protein · chain B against A, TM-score 0.92
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0A0H5
- Elsewhere: RCSB PDB 6OV1 · PDBe 6OV1 · UniProt P0A0H5
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