Research workbench
Asymmetric focused reconstruction of human norovirus GI.7 houston strain vlp asymmetric unit in T=3 symmetry
Analyse Asymmetric focused reconstruction of human norovirus GI.7 houston strain vlp… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6OU9
- Type
- protein
- Length
- 1,473 residues
- Chains
- 3
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Major capsid protein
- UniProt
- G8FL04
- Pockets
- 12 · best druggability 0.84
Structure
electron microscopy · 3 distinct chains · 6% helix, 32% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| B | Major capsid protein | protein | 507 | 6% helix, 31% strand | G8FL04 |
| A | Major capsid protein | protein | 483 | 6% helix, 32% strand | G8FL04 |
| C | Major capsid protein | protein | 483 | 6% helix, 34% strand | G8FL04 |
Pockets
12 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 793 | 0.84 | 0.87 | 100 | empty |
| 2 | 700 | 0.80 | 0.85 | 77 | empty |
| 3 | 161 | 0.73 | 0.91 | 26 | empty |
| 4 | 419 | 0.71 | 0.82 | 62 | empty |
| 5 | 76 | 0.67 | 0.93 | 20 | empty |
Interfaces
3 interfaces between chains.
- B–A · 2340 Ų buried · 9 hydrogen bonds · protein-protein
- B–C · 1637 Ų buried · 5 hydrogen bonds · protein-protein
- A–C · 1111 Ų buried · 7 hydrogen bonds · protein-protein
Compared structures
- 6OU9 · Asymmetric focused reconstruction of human norovirus GI.7 Houston strain VLP asymmetric… · the same entry in another collection · chain B against B, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt G8FL04
- Elsewhere: RCSB PDB 6OU9 · PDBe 6OU9 · UniProt G8FL04
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