Research workbench
Crystal structure of desulfovibrio vulgaris carbon monoxide dehydrogenase with the D-cluster ligating cysteines mutated to alanines, coexpressed with cooc, as-isolated
Analyse Crystal structure of desulfovibrio vulgaris carbon monoxide dehydrogenase with… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6ONS
- Type
- protein
- Length
- 621 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Carbon monoxide dehydrogenase
- EC
- 1.2.7.4
- UniProt
- A0A0E0T3I2
- Ligands
- SF4, XCC
- Pockets
- 5 · best druggability 0.73
Structure
x-ray diffraction · 1 distinct chain · 52% helix, 11% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Carbon monoxide dehydrogenase (EC 1.2.7.4) | protein | 621 | 52% helix, 11% strand | A0A0E0T3I2 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 61 | 0.73 | 0.98 | 25 | empty |
| 2 | 66 | 0.49 | 0.85 | 17 | empty |
| 3 | 171 | 0.44 | 0.74 | 29 | empty |
| 4 | 53 | 0.33 | 0.77 | 12 | empty |
| 5 | 57 | 0.27 | 0.73 | 13 | empty |
Compared structures
- 6ONS · Crystal structure of Desulfovibrio vulgaris carbon monoxide dehydrogenase with the… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A0E0T3I2
- Elsewhere: RCSB PDB 6ONS · PDBe 6ONS · UniProt A0A0E0T3I2
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.