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Crystal structure of aspergillus fumigatus EGA3

Analyse Crystal structure of aspergillus fumigatus EGA3 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6OJ1
Type: protein
Length: 251 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Endo alpha-1,4 polygalactosaminidase
UniProt: Q4WX16
Ligands: NAG, MAN, BMA, K
Pockets: 1 · best druggability 0.53

Structure

x-ray diffraction · 1 distinct chain · 32% helix, 22% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Endo alpha-1,4 polygalactosaminidase	protein	251	32% helix, 22% strand	Q4WX16

Ligands and binding sites

NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 9 copies · chains A
MAN · alpha-D-mannopyranose · sugar · 5 copies · chains A
BMA · beta-D-mannopyranose · sugar · 2 copies · chains A
K · Potassium ion · metal · chains A
EDO · 1,2-ethanediol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	311	0.53	0.74	37	K

Modifications

Observed in the structure: 5 glycan, 3 disulfide (N-glycosylation, disulfide).

Compared structures

6OJ1 · Crystal Structure of Aspergillus fumigatus Ega3 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q4WX16
Elsewhere: RCSB PDB 6OJ1 · PDBe 6OJ1 · UniProt Q4WX16

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