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Structure of aedes aegypti OBP22 in the complex with linoleic acid

Analyse Structure of aedes aegypti OBP22 in the complex with linoleic acid in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6OGH
Type: protein
Length: 121 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: AAEL005772-pa
UniProt: Q1HRL7
Ligands: EIC, CD, CO
Pockets: 1 · best druggability 0.80

Structure

x-ray diffraction · 1 distinct chain · 64% helix, 3% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	AAEL005772-pa	protein	121	64% helix, 3% strand	Q1HRL7

Ligands and binding sites

EIC · Linoleic acid · ligand · chains A
CD · Cadmium ion · metal · 2 copies · chains A
CO · Cobalt (II) ion · metal · chains A
EPE · 4-(2-hydroxyethyl)-1-piperazine ethanesulfonic acid · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	219	0.80	0.92	31	EIC

Modifications

Observed in the structure: 3 disulfide (disulfide).

Compared structures

6OGH · Structure of Aedes aegypti OBP22 in the complex with linoleic acid · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q1HRL7
Elsewhere: RCSB PDB 6OGH · PDBe 6OGH · UniProt Q1HRL7

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