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Crystal structure of PHO7 complex with PHO1 promoter site 2

Analyse Crystal structure of PHO7 complex with PHO1 promoter site 2 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
6O19
Type
protein + DNA
Length
99 residues
Chains
3
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Transcription factor PHO7; DNA (5'- D(*TP*TP*AP*TP*TP*CP*GP*GP*AP*AP*AP*TP*TP*AP*AP*AP*AP*…
UniProt
O13658
Ligands
ZN

Structure

x-ray diffraction · 3 distinct chains · 20% helix, 0% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ATranscription factor PHO7protein5920% helix, 0% strandO13658
CDNA (5'- D(*TP*TP*AP*TP*TP*CP*GP*GP*AP*AP*AP*TP*TP*AP*AP*AP*AP*AP*CP*A)-3')dna20——
BDNA (5'- D(*GP*TP*TP*TP*TP*TP*AP*AP*TP*TP*TP*CP*CP*GP*AP*AP*TP*AP*AP*T)-3')dna20——

Ligands and binding sites

  • ZN · Zinc ion · metal · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

3 interfaces between chains.

  • C–B · 881 Ų buried · 67 hydrogen bonds · nucleic-nucleic
  • A–B · 855 Ų buried · 18 hydrogen bonds · protein-nucleic
  • A–C · 797 Ų buried · 18 hydrogen bonds · protein-nucleic

Compared structures

  • 6O19 · Crystal Structure of Pho7 complex with pho1 promoter site 2 · the same entry in another collection · chain A against A, TM-score 1.00
  • O13658 · AlphaFold monomer V2.0 prediction for uncharacterized transcriptional regulatory protein… · a predicted model of the same protein · chain A against A, TM-score 0.62

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