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Respiratory syncytial virus fusion protein N-terminal heptad repeat DOMAIN+VIQKI

Analyse Respiratory syncytial virus fusion protein N-terminal heptad repeat DOMAIN+VIQKI in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
6NTX
Type
protein
Length
143 residues
Chains
4
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Fusion glycoprotein F0
UniProt
A0A1U8ZTH8, A0A1V0BZ41
Ligands
ACE, NH2

Structure

x-ray diffraction · 4 distinct chains · 92% helix, 0% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AFusion glycoprotein F0protein4395% helix, 0% strandA0A1U8ZTH8
BFusion glycoprotein F0protein3995% helix, 0% strandA0A1U8ZTH8
CFusion glycoprotein F0protein3488% helix, 0% strandA0A1V0BZ41
DFusion glycoprotein F0protein2789% helix, 0% strandA0A1V0BZ41

Ligands and binding sites

  • ACE · Acetyl group · ligand · chains B
  • NH2 · Amino group · ion · chains C

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

4 interfaces between chains.

  • A–C · 722 Ų buried · 5 hydrogen bonds · protein-protein
  • B–D · 468 Ų buried · 3 hydrogen bonds · protein-protein
  • B–C · 223 Ų buried · 5 hydrogen bonds · protein-protein
  • C–D · 148 Ų buried · 2 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 1 covalent (covalent ligand).

Compared structures

  • 6NTX · Respiratory syncytial virus fusion protein N-terminal heptad repeat domain+VIQKI · the same entry in another collection · chain A against A, TM-score 1.00

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