Research workbench
Tetr family transcriptional regulator cifr C99T-C107S-C181R cysteines mutant complexed with 26BP double-strand operator DNA
Analyse Tetr family transcriptional regulator cifr C99T-C107S-C181R cysteines mutant… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6NSM
- Type
- protein + DNA
- Length
- 438 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Copper outer membrane regulator; DNA (26-mer)
- UniProt
- A0A0F6UBT4
- Pockets
- 7 · best druggability 0.74
Structure
x-ray diffraction · 4 distinct chains · 71% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Copper outer membrane regulator | protein | 194 | 70% helix, 0% strand | A0A0F6UBT4 |
| B | Copper outer membrane regulator | protein | 192 | 72% helix, 0% strand | A0A0F6UBT4 |
| C | DNA (26-mer) | dna | 26 | — | — |
| D | DNA (26-mer) | dna | 26 | — | — |
Pockets
7 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 70 | 0.74 | 0.98 | 23 | empty |
| 2 | 607 | 0.72 | 0.80 | 54 | empty |
| 3 | 137 | 0.63 | 0.86 | 31 | empty |
| 4 | 87 | 0.34 | 0.74 | 14 | empty |
| 5 | 85 | 0.33 | 0.74 | 13 | empty |
Interfaces
6 interfaces between chains.
- A–B · 1834 Ų buried · 34 hydrogen bonds · protein-protein
- C–D · 1102 Ų buried · 95 hydrogen bonds · nucleic-nucleic
- A–D · 578 Ų buried · 11 hydrogen bonds · protein-nucleic
- A–C · 540 Ų buried · 9 hydrogen bonds · protein-nucleic
- B–C · 483 Ų buried · 6 hydrogen bonds · protein-nucleic
Compared structures
- 6NSM · TetR family transcriptional regulator CifR C99T-C107S-C181R Cysteines mutant complexed… · the same entry in another collection · chain B against B, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A0F6UBT4
- Elsewhere: RCSB PDB 6NSM · PDBe 6NSM · UniProt A0A0F6UBT4
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.