Research workbench
Structure of the NKCC1 ctd
Analyse Structure of the NKCC1 ctd in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6NPJ
- Type
- protein
- Length
- 768 residues
- Chains
- 2
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Sodium-potassium-chloride cotransporter 1
- UniProt
- C7EA90
- Pockets
- 16 · best druggability 0.79
Structure
electron microscopy · 1 distinct chain · 38% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| C, B | Sodium-potassium-chloride cotransporter 1 | protein | 384 | 38% helix, 16% strand | C7EA90 |
Pockets
16 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 395 | 0.79 | 0.88 | 43 | empty |
| 2 | 435 | 0.76 | 0.85 | 39 | empty |
| 3 | 231 | 0.57 | 0.79 | 24 | empty |
| 4 | 247 | 0.55 | 0.77 | 25 | empty |
| 5 | 109 | 0.51 | 0.81 | 21 | empty |
Interfaces
1 interface between chains.
- C–B · 2881 Ų buried · 13 hydrogen bonds · protein-protein
Compared structures
- 6NPJ · Structure of the NKCC1 CTD · the same entry in another collection · chain C against C, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt C7EA90
- Elsewhere: RCSB PDB 6NPJ · PDBe 6NPJ · UniProt C7EA90
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