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Crystal structure of murine MXRA8 ectodomain
Analyse Crystal structure of murine MXRA8 ectodomain in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6NK3
- Type
- protein
- Length
- 528 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Matrix remodeling-associated protein 8
- UniProt
- Q9DBV4
- Pockets
- 5 · best druggability 0.61
Structure
x-ray diffraction · 2 distinct chains · 11% helix, 44% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Matrix remodeling-associated protein 8 | protein | 263 | 10% helix, 44% strand | Q9DBV4 |
| B | Matrix remodeling-associated protein 8 | protein | 265 | 12% helix, 44% strand | Q9DBV4 |
Pockets
5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 321 | 0.61 | 0.78 | 48 | empty |
| 2 | 77 | 0.48 | 0.83 | 17 | empty |
| 3 | 104 | 0.42 | 0.78 | 18 | empty |
| 4 | 64 | 0.34 | 0.77 | 21 | empty |
| 5 | 70 | 0.30 | 0.74 | 14 | empty |
Interfaces
1 interface between chains.
- A–B · 710 Ų buried · 4 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 6 disulfide (disulfide).
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9DBV4
- Elsewhere: RCSB PDB 6NK3 · PDBe 6NK3 · UniProt Q9DBV4
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