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2.60 ångström resolution crystal structure of periplasmic binding and sugar binding domain of laci family protein from klebsiella pneumoniae.

Analyse 2.60 ångström resolution crystal structure of periplasmic binding and sugar… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6NDI
Type: protein
Length: 544 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Transcriptional regulator
UniProt: A0A2W0LW10
Pockets: 4 · best druggability 0.73

Structure

x-ray diffraction · 2 distinct chains · 36% helix, 23% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Transcriptional regulator	protein	273	36% helix, 23% strand	A0A2W0LW10
B	Transcriptional regulator	protein	271	36% helix, 23% strand	A0A2W0LW10

Pockets

4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	103	0.73	0.94	20	empty
2	446	0.72	0.82	67	empty
3	308	0.72	0.85	36	empty
4	79	0.35	0.75	13	empty

Interfaces

1 interface between chains.

A–B · 1738 Å² buried · 17 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 10 modified (engineered).

Compared structures

6NDI · Crystal Structure of the Sugar Binding Domain of LacI Family Protein from Klebsiella… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A2W0LW10
Elsewhere: RCSB PDB 6NDI · PDBe 6NDI · UniProt A0A2W0LW10

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