Research workbench
Mcherry pH sensitive mutant - M66T (mcherrytyg)
Analyse Mcherry pH sensitive mutant - M66T (mcherrytyg) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6MZ3
- Type
- protein
- Length
- 219 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- PAMCHERRY1 protein
- UniProt
- D1MPT3
- Ligands
- CRO
- Pockets
- 2 · best druggability 0.77
Structure
x-ray diffraction · 1 distinct chain · 6% helix, 57% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | PAMCHERRY1 protein | protein | 219 | 6% helix, 57% strand | D1MPT3 |
Ligands and binding sites
- CRO · {2-[(1R,2R)-1-amino-2-hydroxypropyl]-4-(4-hydroxybenzylidene)-5-oxo-4,5-dihydro-1H-imidazol-1-yl}acetic acid · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 101 | 0.77 | 0.98 | 26 | CRO |
| 2 | 50 | 0.28 | 0.75 | 15 | empty |
Modifications
Observed in the structure: 2 cofactor (chromophore).
Compared structures
- 6MZ3 · mCherry pH sensitive mutant - M66T (mCherryTYG) · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt D1MPT3
- Elsewhere: RCSB PDB 6MZ3 · PDBe 6MZ3 · UniProt D1MPT3
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