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Structure of human CLASP1 TOG1

Analyse Structure of human CLASP1 TOG1 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6MQ5
Type: protein
Length: 468 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Clip-associating protein 1
UniProt: Q7Z460
Pockets: 2 · best druggability 0.74

Structure

x-ray diffraction · 1 distinct chain · 76% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Clip-associating protein 1	protein	234	76% helix, 0% strand	Q7Z460

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	776	0.74	0.79	96	empty
2	54	0.26	0.74	14	empty

Interfaces

1 interface between chains.

A–B · 781 Å² buried · 4 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 14 modified (engineered).

Compared structures

6MQ5 · Structure of human CLASP1 TOG1 · the same entry in another collection · chain A against A, TM-score 1.00
Q7Z460 · AlphaFold monomer V2.0 prediction for clip-associating protein 1 (Q7Z460) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q7Z460
Elsewhere: RCSB PDB 6MQ5 · PDBe 6MQ5 · UniProt Q7Z460

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