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Crystal structure of penicillin binding protein 5 (PBP5) from enterococcus faecium in the open conformation

Analyse Crystal structure of penicillin binding protein 5 (PBP5) from enterococcus… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6MKA
Type: protein
Length: 640 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Penicillin binding protein 5 (PBP5)
UniProt: A0A075Q0W3
Ligands: SO4
Pockets: 5 · best druggability 0.51

Structure

x-ray diffraction · 1 distinct chain · 32% helix, 25% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Penicillin binding protein 5 (PBP5)	protein	640	32% helix, 25% strand	A0A075Q0W3

Ligands and binding sites

SO4 · Sulfate ion · ion · 17 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	106	0.51	0.82	20	empty
2	193	0.49	0.76	31	empty
3	141	0.41	0.75	28	empty
4	78	0.36	0.76	19	SO4
5	69	0.32	0.75	17	empty

Compared structures

6MKA · Crystal structure of penicillin binding protein 5 (PBP5) from Enterococcus faecium in the… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A075Q0W3
Elsewhere: RCSB PDB 6MKA · PDBe 6MKA · UniProt A0A075Q0W3

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