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Structural characterization of a 39 residue synthetic peptide containing the two zinc binding domains from the HIV-1 P7 nucleocapsid protein by CD and NMR spectroscopy

Analyse Structural characterization of a 39 residue synthetic peptide containing the… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
1NCP
Type
protein
Length
35 residues
Chains
2
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
HIV-1 P7 nucleocapsid protein
UniProt
P04585, P24740
Ligands
ZN

Structure

solution nmr · 2 distinct chains · 0% helix, 83% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
NHIV-1 P7 nucleocapsid proteinprotein170% helix, 88% strandP04585
CHIV-1 P7 nucleocapsid proteinprotein180% helix, 78% strandP24740

Ligands and binding sites

  • ZN · Zinc ion · metal · 2 copies · chains N, C

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

  • N–C · 923 Ų buried · 117 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 3 disulfide (disulfide).

Compared structures

  • 1NCP · Structural characterization of a 39 residue synthetic peptide containing the two zinc… · the same entry in another collection · chain N against N, TM-score 1.00

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