Research workbench
Structure of candida glabrata CSM1: S. cerevisiae DSN1 complex
Analyse Structure of candida glabrata CSM1: S. cerevisiae DSN1 complex in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6MJE
- Type
- protein
- Length
- 558 residues
- Chains
- 8
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Monopolin complex subunit CSM1; DSN1P
- UniProt
- A0A0W0CH22, A0A1L4A9Z4
- Pockets
- 6 · best druggability 0.72
Structure
x-ray diffraction · 3 distinct chains · 42% helix, 29% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, C | Monopolin complex subunit CSM1 | protein | 110 | 42% helix, 32% strand | A0A0W0CH22 |
| B, D, F, H | DSN1P | protein | 30 | 43% helix, 7% strand | A0A1L4A9Z4 |
| E, G | Monopolin complex subunit CSM1 | protein | 109 | 42% helix, 32% strand | A0A0W0CH22 |
Pockets
6 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 764 | 0.72 | 0.78 | 90 | empty |
| 2 | 270 | 0.60 | 0.79 | 45 | empty |
| 3 | 166 | 0.54 | 0.80 | 31 | empty |
| 4 | 179 | 0.53 | 0.79 | 38 | empty |
| 5 | 102 | 0.37 | 0.75 | 18 | empty |
Interfaces
10 interfaces between chains.
- C–E · 1554 Ų buried · 11 hydrogen bonds · protein-protein
- A–G · 1542 Ų buried · 9 hydrogen bonds · protein-protein
- E–F · 1416 Ų buried · 18 hydrogen bonds · protein-protein
- G–H · 1396 Ų buried · 22 hydrogen bonds · protein-protein
- A–B · 1388 Ų buried · 20 hydrogen bonds · protein-protein
Compared structures
- 6MJE · Structure of Candida glabrata Csm1: S. cerevisiae Dsn1 complex · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A0W0CH22
- Every structure of UniProt A0A1L4A9Z4
- Elsewhere: RCSB PDB 6MJE · PDBe 6MJE · UniProt A0A0W0CH22 · UniProt A0A1L4A9Z4
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