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Crystal structure of ketosynthase nine from bacillaene polyketide synthase in bacillus amyloliquefaciens

Analyse Crystal structure of ketosynthase nine from bacillaene polyketide synthase in… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6MHK
Type: protein
Length: 1,070 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Polyketide synthase
UniProt: Q1RS71
Pockets: 10 · best druggability 0.74

Structure

x-ray diffraction · 2 distinct chains · 38% helix, 21% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Polyketide synthase	protein	536	38% helix, 21% strand	Q1RS71
B	Polyketide synthase	protein	534	37% helix, 21% strand	Q1RS71

Pockets

10 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	422	0.74	0.84	48	empty
2	441	0.74	0.84	49	empty
3	500	0.66	0.78	49	empty
4	477	0.65	0.77	51	empty
5	107	0.39	0.76	19	empty

Interfaces

1 interface between chains.

A–B · 2408 Å² buried · 37 hydrogen bonds · protein-protein

Compared structures

6MHK · Crystal structure of ketosynthase nine from bacillaene polyketide synthase in Bacillus… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q1RS71
Elsewhere: RCSB PDB 6MHK · PDBe 6MHK · UniProt Q1RS71

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