Research workbench

Crystal structure of caenorhabditis elegans dicer-related helicase 3 (drh-3) N-terminal domain

Analyse Crystal structure of caenorhabditis elegans dicer-related helicase 3 (drh-3)… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6M6Q
Type: protein
Length: 622 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Dicer related helicase
UniProt: Q93413
Pockets: 4 · best druggability 0.80

Structure

x-ray diffraction · 2 distinct chains · 66% helix, 1% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Dicer related helicase	protein	307	64% helix, 1% strand	Q93413
B	Dicer related helicase	protein	315	67% helix, 1% strand	Q93413

Pockets

4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	792	0.80	0.83	80	empty
2	136	0.41	0.75	15	empty
3	74	0.33	0.75	18	empty
4	67	0.30	0.73	15	empty

Interfaces

1 interface between chains.

A–B · 914 Å² buried · 8 hydrogen bonds · protein-protein

Compared structures

6M6Q · Crystal structure of Caenorhabditis elegans Dicer-related helicase 3 (DRH-3) N-terminal… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q93413
Elsewhere: RCSB PDB 6M6Q · PDBe 6M6Q · UniProt Q93413

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.