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Crystal structure of bptf-brd with ligand DCBPIN5 bound

Analyse Crystal structure of bptf-brd with ligand DCBPIN5 bound in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6LU5
Type: protein
Length: 108 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Nucleosome-remodeling factor subunit bptf
UniProt: J3QQQ8
Ligands: EUO
Pockets: 1 · best druggability 0.53

Structure

x-ray diffraction · 1 distinct chain · 64% helix, 2% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Nucleosome-remodeling factor subunit bptf	protein	108	64% helix, 2% strand	J3QQQ8

Ligands and binding sites

EUO · 6-(1H-indol-5-yl)-N-methyl-2-methylsulfonyl-pyrimidin-4-amine · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	118	0.53	0.82	20	EUO

Compared structures

6LU5 · Crystal structure of BPTF-BRD with ligand DCBPin5 bound · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt J3QQQ8
Elsewhere: RCSB PDB 6LU5 · PDBe 6LU5 · UniProt J3QQQ8

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