Research workbench
Crystal structure of gfpuv complexed with the nanobody LAG16 at 1.67 angstron resolution
Analyse Crystal structure of gfpuv complexed with the nanobody LAG16 at 1.67 angstron… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6LR7
- Type
- protein
- Length
- 356 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Green fluorescient protein UV; Nanobody LAG16
- Ligands
- CRO
- Pockets
- 2 · best druggability 0.76
Structure
x-ray diffraction · 2 distinct chains · 12% helix, 51% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Green fluorescient protein UV | protein | 231 | 12% helix, 53% strand | — |
| B | Nanobody LAG16 | protein | 125 | 11% helix, 48% strand | — |
Ligands and binding sites
- CRO · {2-[(1R,2R)-1-amino-2-hydroxypropyl]-4-(4-hydroxybenzylidene)-5-oxo-4,5-dihydro-1H-imidazol-1-yl}acetic acid · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 93 | 0.76 | 0.97 | 29 | CRO |
| 2 | 52 | 0.27 | 0.74 | 12 | empty |
Interfaces
1 interface between chains.
- A–B · 735 Ų buried · 22 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 2 cofactor, 1 disulfide (chromophore, disulfide).
Compared structures
- 6LR7 · Crystal structure of GFPuv complexed with the nanobody LaG16 at 1.67 Angstron resolution · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 6LR7 · PDBe 6LR7
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