Research workbench

Crystal structure of chicken TCR for 2.0

Analyse Crystal structure of chicken TCR for 2.0 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6LIR
Type: protein
Length: 833 residues
Chains: 4
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: TCR alpha chain; TCR beta chain
Pockets: 9 · best druggability 0.65

Structure

x-ray diffraction · 3 distinct chains · 4% helix, 54% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	TCR alpha chain	protein	195	3% helix, 50% strand	—
B, D	TCR beta chain	protein	222	6% helix, 56% strand	—
C	TCR alpha chain	protein	194	3% helix, 56% strand	—

Pockets

9 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	258	0.65	0.82	36	empty
2	238	0.64	0.82	29	empty
3	192	0.61	0.83	37	empty
4	186	0.61	0.82	36	empty
5	203	0.55	0.79	27	empty

Interfaces

3 interfaces between chains.

A–B · 2160 Å² buried · 32 hydrogen bonds · protein-protein
C–D · 1993 Å² buried · 32 hydrogen bonds · protein-protein
B–D · 1042 Å² buried · 19 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 8 disulfide (disulfide).

Compared structures

6LIR · crystal structure of chicken TCR for 2.0 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 6LIR · PDBe 6LIR

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.