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Crystal structure of ugt transferase MUTANT2

Analyse Crystal structure of ugt transferase MUTANT2 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6L8W
Type: protein
Length: 438 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Glycosyltransferase
EC: 2.4.1.-
UniProt: K7NBW3
Pockets: 4 · best druggability 0.76

Structure

x-ray diffraction · 1 distinct chain · 45% helix, 13% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Glycosyltransferase (EC 2.4.1.-)	protein	438	45% helix, 13% strand	K7NBW3

Pockets

4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	929	0.76	0.79	87	empty
2	289	0.57	0.77	40	empty
3	98	0.46	0.79	14	empty
4	57	0.40	0.81	13	empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

6L8W · Crystal structure of ugt transferase mutant2 · the same entry in another collection · chain A against A, TM-score 1.00
K7NBW3 · AlphaFold monomer V2.0 prediction for mogroside ie synthase (K7NBW3) · a predicted model of the same protein · chain A against A, TM-score 0.96

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt K7NBW3
Elsewhere: RCSB PDB 6L8W · PDBe 6L8W · UniProt K7NBW3

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