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Structure of severe fever with thrombocytopenia syndrome virus L protein

Analyse Structure of severe fever with thrombocytopenia syndrome virus L protein in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6L42
Type: protein
Length: 1,864 residues
Chains: 1
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: RNA polymerase
UniProt: I0DF35
Ligands: MG
Pockets: 20 · best druggability 0.84

Structure

electron microscopy · 1 distinct chain · 35% helix, 9% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	RNA polymerase	protein	1864	35% helix, 9% strand	I0DF35

Ligands and binding sites

MG · Magnesium ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

20 pockets found on a 1 Å grid, 20 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1081	0.84	0.85	104	empty
2	925	0.83	0.85	86	empty
3	1081	0.81	0.82	110	empty
4	131	0.77	0.96	29	empty
5	930	0.76	0.79	83	MG

Modifications

Observed in the structure: 1 isopeptide (isopeptide).

Compared structures

6L42 · Structure of severe fever with thrombocytopenia syndrome virus L protein · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt I0DF35
Elsewhere: RCSB PDB 6L42 · PDBe 6L42 · UniProt I0DF35

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