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Crystal structure of the sixth PDZ domain of GRIP1 in complex with liprin C-terminal peptide

Analyse Crystal structure of the sixth PDZ domain of GRIP1 in complex with liprin… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1N7F
Type: protein
Length: 188 residues
Chains: 4
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: AMPA receptor interacting protein grip; 8-mer peptide from interacting protein (liprin)
UniProt: P97879

Structure

x-ray diffraction · 2 distinct chains · 14% helix, 37% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	AMPA receptor interacting protein grip	protein	86	15% helix, 36% strand	P97879
C, D	8-mer peptide from interacting protein (liprin)	protein	8	0% helix, 50% strand	—

Interfaces

3 interfaces between chains.

A–B · 648 Å² buried · 9 hydrogen bonds · protein-protein
B–D · 503 Å² buried · 13 hydrogen bonds · protein-protein
A–C · 496 Å² buried · 12 hydrogen bonds · protein-protein

Compared structures

1N7F · Crystal structure of the sixth PDZ domain of GRIP1 in complex with liprin C-terminal… · the same entry in another collection · chain A against A, TM-score 1.00
P97879 · AlphaFold monomer V2.0 prediction for glutamate receptor-interacting protein 1 (P97879) · a predicted model of the same protein · chain A against A, TM-score 0.94

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P97879
Elsewhere: RCSB PDB 1N7F · PDBe 1N7F · UniProt P97879

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