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The structure of the M. tb toxin mazf-MT1

Analyse The structure of the M. tb toxin mazf-MT1 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6KYS
Type: protein
Length: 240 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Endoribonuclease MAZF9
EC: 3.1.-.-
UniProt: P71650
Pockets: 2 · best druggability 0.45

Structure

x-ray diffraction · 2 distinct chains · 29% helix, 33% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Endoribonuclease MAZF9 (EC 3.1.-.-)	protein	118	30% helix, 33% strand	P71650
B	Endoribonuclease MAZF9 (EC 3.1.-.-)	protein	122	28% helix, 32% strand	P71650

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	165	0.45	0.75	22	empty
2	110	0.40	0.76	18	empty

Interfaces

1 interface between chains.

A–B · 1657 Å² buried · 35 hydrogen bonds · protein-protein

Compared structures

6KYS · The structure of the M. tb toxin MazF-mt1 · the same entry in another collection · chain B against B, TM-score 1.00
P71650 · AlphaFold monomer V2.0 prediction for endoribonuclease MAZF9 (P71650) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P71650
Elsewhere: RCSB PDB 6KYS · PDBe 6KYS · UniProt P71650

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