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Average structure of the interferon-binding ectodomain of the human type I interferon receptor

Analyse Average structure of the interferon-binding ectodomain of the human type I… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1N6V
Type: protein
Length: 212 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Interferon-ALPHA/BETA receptor beta chain
UniProt: P48551
Pockets: 1 · best druggability 0.57

Structure

solution nmr · 1 distinct chain · 3% helix, 42% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Interferon-ALPHA/BETA receptor beta chain	protein	212	3% helix, 42% strand	P48551

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	143	0.57	0.82	23	empty

Modifications

Observed in the structure: 3 disulfide (disulfide).

Compared structures

1N6V · Average structure of the interferon-binding ectodomain of the human type I interferon… · the same entry in another collection · chain A against A, TM-score 1.00
P48551 · AlphaFold monomer V2.0 prediction for interferon ALPHA/BETA receptor 2 (P48551) · a predicted model of the same protein · chain A against A, TM-score 0.79

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P48551
Elsewhere: RCSB PDB 1N6V · PDBe 1N6V · UniProt P48551

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