Research workbench
Human parallel stranded 7-mer G-quadruplex complexed with 2 adriamycin (DM2) molecules
Analyse Human parallel stranded 7-mer G-quadruplex complexed with 2 adriamycin (DM2)… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6KN4
- Type
- DNA
- Length
- 28 nucleotides
- Chains
- 4
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- DNA (5'-D(*TP*TP*AP*GP*GP*GP*T)-3')
- Ligands
- DM2
Structure
solution nmr · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D | DNA (5'-D(*TP*TP*AP*GP*GP*GP*T)-3') | dna | 7 | — | — |
Ligands and binding sites
- DM2 · Doxorubicin · ligand · 2 copies · chains A, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Interfaces
6 interfaces between chains.
- B–C · 373 Ų buried · 7 hydrogen bonds · nucleic-nucleic
- A–D · 323 Ų buried · 10 hydrogen bonds · nucleic-nucleic
- C–D · 314 Ų buried · 10 hydrogen bonds · nucleic-nucleic
- A–B · 303 Ų buried · 11 hydrogen bonds · nucleic-nucleic
- B–D · 65 Ų buried · 0 hydrogen bonds · nucleic-nucleic
Compared structures
- 6KN4 · Human parallel stranded 7-mer G-quadruplex complexed with 2 adriamycin (DM2) molecules · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 6KN4 · PDBe 6KN4
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.