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Extended hect domain of UBE3C E3 ligase

Analyse Extended hect domain of UBE3C E3 ligase in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6K2C
Type: protein
Length: 298 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Ubiquitin-protein ligase E3C
EC: 2.3.2.26
UniProt: Q15386
Pockets: 1 · best druggability 0.57

Structure

x-ray diffraction · 1 distinct chain · 51% helix, 10% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Ubiquitin-protein ligase E3C (EC 2.3.2.26)	protein	298	51% helix, 10% strand	Q15386

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	130	0.57	0.83	35	empty

Compared structures

6K2C · Extended Hect domain of UBE3C E3 Ligase · the same entry in another collection · chain A against A, TM-score 1.00
Q15386 · AlphaFold monomer V2.0 prediction for ubiquitin-protein ligase E3C (Q15386) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q15386
Elsewhere: RCSB PDB 6K2C · PDBe 6K2C · UniProt Q15386

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