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TEL1 kinase butterfly symmetric dimer

Analyse TEL1 kinase butterfly symmetric dimer in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
6JXC
Type
protein
Length
2,345 residues
Chains
1
Method
electron microscopy
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
SERINE/THREONINE-protein kinase TEL1
EC
2.7.11.1
UniProt
P38110
Pockets
20 · best druggability 0.85

Structure

electron microscopy · 1 distinct chain · 59% helix, 0% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ASERINE/THREONINE-protein kinase TEL1 (EC 2.7.11.1)protein234559% helix, 0% strandP38110

Pockets

20 pockets found on a 1 Å grid, 20 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
111750.850.85113empty
29410.840.86103empty
35920.840.8977empty
44040.780.8770empty
53640.760.8767empty

Compared structures

  • 6JXC · Tel1 kinase butterfly symmetric dimer · the same entry in another collection · chain A against A, TM-score 1.00

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