Research workbench
Crystal structure of YAP1 and dendrin complex 2
Analyse Crystal structure of YAP1 and dendrin complex 2 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6JK1
- Type
- protein
- Length
- 182 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- DENDRIN,TRANSCRIPTIONAL coactivator YAP1
- UniProt
- Q80TS7, P46938
- Pockets
- 1 · best druggability 0.63
Structure
x-ray diffraction · 2 distinct chains · 0% helix, 31% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DENDRIN,TRANSCRIPTIONAL coactivator YAP1 | protein | 96 | 0% helix, 29% strand | Q80TS7, P46938 |
| B | DENDRIN,TRANSCRIPTIONAL coactivator YAP1 | protein | 86 | 0% helix, 34% strand | Q80TS7, P46938 |
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 521 | 0.63 | 0.75 | 27 | empty |
Interfaces
1 interface between chains.
- A–B · 924 Ų buried · 8 hydrogen bonds · protein-protein
Compared structures
- 6JK1 · Crystal Structure of YAP1 and Dendrin complex 2 · the same entry in another collection · chain A against A, TM-score 1.00
- P46938 · AlphaFold monomer V2.0 prediction for transcriptional coactivator YAP1 (P46938) · a predicted model of the same protein · chain B against A, TM-score 0.41
- Q80TS7 · AlphaFold monomer V2.0 prediction for dendrin (Q80TS7) · a predicted model of the same protein · chain A against A, TM-score 0.24
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q80TS7
- Every structure of UniProt P46938
- Elsewhere: RCSB PDB 6JK1 · PDBe 6JK1 · UniProt Q80TS7 · UniProt P46938
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.