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Crystal structure of a free scfv molecule from a group 2 influenza a viruses ha binding antibody AF4H1K1
Analyse Crystal structure of a free scfv molecule from a group 2 influenza a viruses ha… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6J9O
- Type
- protein
- Length
- 238 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Heavy chain of AF4H1K1 scfv; Light chain of AF4H1K1 scfv
- Pockets
- 2 · best druggability 0.37
Structure
x-ray diffraction · 2 distinct chains · 6% helix, 48% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| H | Heavy chain of AF4H1K1 scfv | protein | 130 | 7% helix, 46% strand | — |
| L | Light chain of AF4H1K1 scfv | protein | 108 | 6% helix, 50% strand | — |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 107 | 0.37 | 0.74 | 19 | empty |
| 2 | 67 | 0.28 | 0.73 | 17 | empty |
Interfaces
1 interface between chains.
- H–L · 834 Ų buried · 11 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 2 disulfide (disulfide).
Compared structures
- 6J9O · Crystal structure of a free scFv molecule from a group 2 influenza A viruses HA binding… · the same entry in another collection · chain H against H, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 6J9O · PDBe 6J9O
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