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Crystal structure of card-only protein in frog virus 3

Analyse Crystal structure of card-only protein in frog virus 3 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6J52
Type: protein
Length: 375 residues
Chains: 4
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Caspase recruitment domain-only protein
UniProt: W8SPG9
Pockets: 1 · best druggability 0.52

Structure

x-ray diffraction · 2 distinct chains · 77% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B, C	Caspase recruitment domain-only protein	protein	94	77% helix, 0% strand	W8SPG9
D	Caspase recruitment domain-only protein	protein	93	77% helix, 0% strand	W8SPG9

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	230	0.52	0.76	33	empty

Interfaces

5 interfaces between chains.

C–D · 3429 Å² buried · 36 hydrogen bonds · protein-protein
A–B · 3385 Å² buried · 38 hydrogen bonds · protein-protein
A–D · 136 Å² buried · 2 hydrogen bonds · protein-protein
B–D · 88 Å² buried · 0 hydrogen bonds · protein-protein
B–C · 45 Å² buried · 1 hydrogen bond · protein-protein

Compared structures

6J52 · Crystal structure of CARD-only protein in frog virus 3 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt W8SPG9
Elsewhere: RCSB PDB 6J52 · PDBe 6J52 · UniProt W8SPG9

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