Research workbench
Ctx-M-64 beta-lactamase mutant-S130T
Analyse Ctx-M-64 beta-lactamase mutant-S130T in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6J25
- Type
- protein
- Length
- 520 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Beta-lactamase
- EC
- 3.5.2.6
- UniProt
- C8CP57
- Pockets
- 2 · best druggability 0.77
Structure
x-ray diffraction · 1 distinct chain · 43% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Beta-lactamase (EC 3.5.2.6) | protein | 260 | 43% helix, 20% strand | C8CP57 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1082 | 0.77 | 0.80 | 125 | empty |
| 2 | 57 | 0.31 | 0.75 | 13 | empty |
Interfaces
1 interface between chains.
- A–B · 585 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 6J25 · CTX-M-64 beta-lactamase mutant-S130T · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt C8CP57
- Elsewhere: RCSB PDB 6J25 · PDBe 6J25 · UniProt C8CP57
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