Research workbench
Crystal structure of a cell division and cell wall biosynthesis protein UPF0040 from mycoplasma pneumoniae: indication of a novel fold with a possible new conserved sequence motif
Analyse Crystal structure of a cell division and cell wall biosynthesis protein UPF0040… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1N0F
- Type
- protein
- Length
- 1,102 residues
- Chains
- 8
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Protein mraz
- UniProt
- P75467
- Pockets
- 11 · best druggability 0.59
Structure
x-ray diffraction · 3 distinct chains · 36% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Protein mraz | protein | 141 | 35% helix, 21% strand | P75467 |
| B | Protein mraz | protein | 139 | 35% helix, 22% strand | P75467 |
| C, D, E, F, G, H | Protein mraz | protein | 137 | 36% helix, 23% strand | P75467 |
Pockets
11 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 73 | 0.59 | 0.89 | 22 | empty |
| 2 | 77 | 0.57 | 0.88 | 24 | empty |
| 3 | 55 | 0.56 | 0.90 | 21 | empty |
| 4 | 88 | 0.54 | 0.85 | 25 | empty |
| 5 | 125 | 0.53 | 0.82 | 30 | empty |
Interfaces
16 interfaces between chains.
- A–B · 1410 Ų buried · 17 hydrogen bonds · protein-protein
- B–C · 1344 Ų buried · 20 hydrogen bonds · protein-protein
- A–H · 1313 Ų buried · 20 hydrogen bonds · protein-protein
- G–H · 1312 Ų buried · 18 hydrogen bonds · protein-protein
- D–E · 1310 Ų buried · 16 hydrogen bonds · protein-protein
Compared structures
- 1N0F · Crystal structure of a cell division and cell wall biosynthesis protein UPF0040 from… · the same entry in another collection · chain H against H, TM-score 1.00
- P75467 · AlphaFold monomer V2.0 prediction for transcriptional regulator mraz (P75467) · a predicted model of the same protein · chain C against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P75467
- Elsewhere: RCSB PDB 1N0F · PDBe 1N0F · UniProt P75467
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.